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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5D
All Species:
23.33
Human Site:
S428
Identified Species:
51.33
UniProt:
Q92835
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92835
NP_001017915.1
1189
133292
S428
K
I
T
S
W
F
L
S
K
G
Q
G
K
T
R
Chimpanzee
Pan troglodytes
XP_526066
929
104074
E193
I
Y
V
I
G
T
Q
E
D
P
L
S
E
K
E
Rhesus Macaque
Macaca mulatta
XP_001114794
1258
138636
S448
N
V
T
S
W
F
T
S
R
G
L
G
K
T
L
Dog
Lupus familis
XP_542327
1264
138869
S454
N
V
T
S
W
F
T
S
K
G
L
G
K
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES52
1191
133524
S431
K
I
T
S
W
F
L
S
K
G
Q
G
K
T
R
Rat
Rattus norvegicus
P97573
1190
133575
S430
K
I
T
S
W
F
L
S
K
G
Q
G
K
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520934
1019
113512
V283
D
K
A
K
A
L
L
V
E
G
S
E
S
T
H
Chicken
Gallus gallus
XP_422567
1182
133482
S427
K
I
T
S
W
F
L
S
K
G
Q
G
K
T
R
Frog
Xenopus laevis
Q6P4S2
1019
115278
V283
V
L
M
E
G
A
A
V
K
H
R
R
S
L
I
Zebra Danio
Brachydanio rerio
Q2I6J1
1266
140353
S432
P
L
G
S
W
I
L
S
R
G
L
G
K
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789838
1327
148052
C426
C
I
T
T
W
L
T
C
Q
G
D
G
K
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.8
41.3
40.9
N.A.
87.8
87.8
N.A.
38.7
68.2
56.5
43.1
N.A.
N.A.
N.A.
N.A.
31
Protein Similarity:
100
77.8
57.5
56.8
N.A.
92.1
92
N.A.
48.5
78.7
67.1
57.9
N.A.
N.A.
N.A.
N.A.
47.3
P-Site Identity:
100
0
60
66.6
N.A.
100
100
N.A.
20
100
6.6
53.3
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
6.6
73.3
73.3
N.A.
100
100
N.A.
26.6
100
20
66.6
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
10
10
0
0
0
0
0
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
10
10
0
0
10
10
0
10
% E
% Phe:
0
0
0
0
0
55
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
19
0
0
0
0
82
0
73
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% H
% Ile:
10
46
0
10
0
10
0
0
0
0
0
0
0
0
10
% I
% Lys:
37
10
0
10
0
0
0
0
55
0
0
0
73
10
0
% K
% Leu:
0
19
0
0
0
19
55
0
0
0
37
0
0
10
28
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
10
0
37
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
19
0
10
10
0
0
46
% R
% Ser:
0
0
0
64
0
0
0
64
0
0
10
10
19
0
0
% S
% Thr:
0
0
64
10
0
10
28
0
0
0
0
0
0
82
0
% T
% Val:
10
19
10
0
0
0
0
19
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
73
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _